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Creatine is synthesized from amino acids in the liver, pancreas and kidneys.

4icu.orgThe discrepancy in the plasma insulin response is most probably because of 8-10 fold variations within the amount of amino acid ingested in the totally different research. The exception to the rule is the DOT1 family, members of which methylate K79 within the globular region of histone H3 and that are structurally not associated to SET-domain proteins 4 - 6 Current work suggests that SET-area-containing proteins methylate a number of proteins in addition to histones (see later)