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The [exception](https://gitea.ws.adacts.com/nicholftm04715/solicitor-article2016/wiki/Six-Super-Meals-You-Should-Have-In-Your-Home-For-The-New-Year) to the rule is the DOT1 family, members of which methylate K79 in the globular region of histone H3 and which are structurally not related to SET-area proteins four - 6 Recent work suggests that SET-domain-containing proteins methylate a couple of proteins in addition to histones (see later) |
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